About our nail fungus test

The symptoms of nail fungus can be similar to the symptoms of a number of other skin diseases, such as psoriasis or eczema.

The symptoms of nail fungus can be similar to the symptoms of a number of other skin diseases, such as psoriasis or eczema. Tight shoes can even cause similar problems. The treatment of nail fungus often takes a very long time. Therefore it is useful to test if you have nail fungus before beginning a long-term treatment.

Our test for nail fungus can give a quick answer on whether nail changes such as nail thickening and dystrophy are caused by dermatophytes. In medical care a diagnosis is made primarily through direct microscopy or fungal culture in the current situation. Dynamic Code has developed a test that detects species within the genus Trichophyton, Microsporum and Epidermophyton by PCR.

We offer cooperative opportunities in which we tailor solutions for each customer. Our concept covers the entire chain from sampling kits and method of analysis to performing analysis and distribution of analytical results.

Simple sampling

Our test for nail fungus is simple to perform. The sampling kit contains sampling material, instructions and return packaging. The test is done by the patient themselves, taking a nail sample at home and sending it to our quality-assured laboratory for DNA analysis. For testing, the patient must have access to a pair of nail scissors. The result of analysis is obtained via our website with a personal code within 3 days after the sample is received at our laboratory.

Background of our test

Nail fungus is caused when dermatophytes, mainly Trichophyton rubrum, attack the nail. In Sweden other species that are commonly present in fungal infections of the nails and skin are T. mentagrophytes, M. canis and E. floccosum. Toenail fungus affects about 10% of adults (Swedish Food and Drug Administration). With nail fungus a thickening of the nail occurs. This usually causes no symptoms but is more of a cosmetic problem. In some cases thickening can lead to the nail pressing on the nail bed and causing pain. Mild attacks on individual nails can be treated with drugs that are applied topically in the form of lacquer or cream. For severe affliction, systemic treatment may be required. The treatment is often long-term and for toenail fungus is only effective in about half of cases. Systemic treatment can cause severe side effects.

Unique method of analysis

The methodology for Dynamic Code’s test is based on PCR. Several research groups have shown that the PCR methodology compares favourably with both microscopy and fungal culture to diagnose nail and skin fungus (Brillowska 2007, Garg 2009 Kondori 2010). Dynamic Code has developed a method that detects multiple species within the genera Trichophyton, Microsporum and Epidermophyton, including detection of T. rubrum, T. mentagrophytes, T. verrucosum, M. canis, M. audonii and E. floccosum.

Information and price quotes

Contact us for more information about our test for nail fungus and for potential collaboration.

Phone: +46(0)13 465 53 20

E-mail: info@dynamiccode.se 

References

Brillowska-Dabrowska A, Saunte DM, Arendrup MC. Five-hour diagnosis of dermatophyte nail infections with specific detection of Trichophyton rubrum. J Clin Microbiol. 2007 Apr;45(4):1200-4

Garg J, Tilak R, Garg A, Prakash P, Gulati AK, Nath G. Rapid detection of dermatophytes from skin and hair. BMC Res Notes. 2009 Apr 18;2:60.

Kondori N, Abrahamsson AL, Ataollahy N, Wennerås C. Comparison of a new commercial test, Dermatophyte-PCR kit, with conventional methods for rapid detection and identification of Trichophyton rubrum in nail specimens. With Mycol. 2010 Nov;48(7):1005-8.

Swedish Food and Drug Administration, Treatment of dermatomycoses – Treatment Recommendation, Information from the Swedish Food and Drug Administration 6:2004

 

To our nail fungus test

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